KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A2
All Species:
17.27
Human Site:
T649
Identified Species:
34.55
UniProt:
O94973
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94973
NP_036437.1
939
103960
T649
P
E
P
A
P
A
S
T
S
A
V
S
T
P
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116794
953
104990
T625
P
E
P
A
P
A
S
T
S
A
M
S
T
P
S
Dog
Lupus familis
XP_533200
1007
111388
A721
P
E
P
A
P
A
S
A
A
S
T
P
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P17427
938
104082
T649
P
E
P
V
P
A
S
T
S
A
A
S
T
P
S
Rat
Rattus norvegicus
P18484
938
104026
T649
P
E
P
V
P
A
S
T
S
A
A
S
T
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
A649
A
E
P
A
S
V
N
A
S
A
V
S
T
P
S
Frog
Xenopus laevis
NP_001089303
939
104392
S650
I
T
E
H
A
P
V
S
T
S
S
T
P
S
P
Zebra Danio
Brachydanio rerio
XP_001922436
930
103267
D650
G
G
G
E
R
G
G
D
N
S
T
I
S
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
N650
Q
N
N
A
L
V
N
N
S
H
S
K
L
N
N
Honey Bee
Apis mellifera
XP_394621
937
104937
T650
A
E
A
P
S
S
V
T
G
A
V
N
N
T
S
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
D649
E
G
S
T
S
L
V
D
F
D
S
T
N
D
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
S712
L
S
K
R
A
N
S
S
R
S
I
M
V
P
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.6
89.3
N.A.
97.2
97.2
N.A.
N.A.
95.3
87.6
84.3
N.A.
69.8
71
66.1
N.A.
Protein Similarity:
100
N.A.
94.5
91.3
N.A.
98.6
98.8
N.A.
N.A.
97.7
94.2
91.1
N.A.
81.4
82.2
78.4
N.A.
P-Site Identity:
100
N.A.
93.3
60
N.A.
86.6
86.6
N.A.
N.A.
66.6
0
0
N.A.
13.3
33.3
0
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
86.6
86.6
N.A.
N.A.
73.3
26.6
20
N.A.
26.6
46.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
42
17
42
0
17
9
50
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
17
0
9
0
0
0
9
0
% D
% Glu:
9
59
9
9
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
17
9
0
0
9
9
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
9
0
0
0
9
9
0
0
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% M
% Asn:
0
9
9
0
0
9
17
9
9
0
0
9
17
9
9
% N
% Pro:
42
0
50
9
42
9
0
0
0
0
0
9
9
59
17
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
9
9
0
25
9
50
17
50
34
25
42
17
9
59
% S
% Thr:
0
9
0
9
0
0
0
42
9
0
17
17
42
17
9
% T
% Val:
0
0
0
17
0
17
25
0
0
0
25
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _